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TETANUS ANTITOXIN
CONCENTRATED/PURIFIED
Cat. #63611 1 x 1500 Unit
(2ml)
Cat. #63614 1 x 15,000 Unit (2ml)
FOR
VETERINARY USE ONLY

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INDICATIONS: Recommended
for use in horses as an aid in the prevention and treatment of
tetanus due to Clostridium tetani. This product is a purified,
concentrated antitoxin, primarily immunoglobulin in nature.
Contains thimerosal as a
preservative.
Recommended for use whenever a
non-immunized horse or one whose tetanus vaccination status is
unknown, suffers a deep penetrating wound that has or may become
contaminated with soil. It provides quick but short term
protection. Antibiotics can be used in conjunction with tetanus
antitoxin or tetanus toxoid and are usually indicated in horses
with wounds.
If horses have received a Tetanus
Toxoid vaccination within the previous 12 months a tetanus Toxoid
booster is preferred over Tetanus Antitoxin for prophylaxis when
these horses have penetrating wounds.
DIRECTIONS: Do
not vaccinate within 21 days before slaughter. Store at 2-7
degrees C. Do not freeze. Use entire contents when first opened.
PRECAUTIONS: Anaphylactoid
reaction may occur following administration of products of this
nature. If noted, administer adrenalin or equivalent.
In the event of accidental human
exposure, consult a physician.
A condition referred to as
"serum hepatitis" infrequently occurs in horses. The
literature associates this partially with the injection of
biologics containing equine serum or tissue. However, at present,
efforts to experimentally reproduce such a condition in horses
have not been successful.
DOSAGE AND ADMINISTRATION:
Tetanus Antitoxin confers immediate passive
immunity lasting about 7 to 14 days. One dose (2 ml) of 1,500
Units administered subcutaneously or intramuscularly in the neck
is the recommended dose for prevention.
Slow healing
puncture wounds or deep abrasions should be administered a second
dose of antitoxin in 7 days and additionally as considered
necessary.
Large doses of Tetanus Antitoxin may provide
beneficial response in horses already affected with tetanus, but
success of treatment is not assured. For treatment; Administer
10,000 to 100,000 Units. However, safety at the 100,000 Unit level
(67 doses or 134 ml) has not been demonstrated.
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